There are few if any reports of people experiencing negative reactions to typical amounts of turmeric in food, and curcumin supplements are generally well tolerated. Turmeric and curcumin are considered safe for most people. Potential Risks and Interactions Curcumin Supplements See Turmeric, Vitamin D, and Coenzyme Q10 for Fibromyalgia
People interested in taking a supplement to treat arthritis pain are advised to consult their health care provider about specific brands and doses. See The Ins and Outs of an Anti-Inflammatory Diet Manufacturers that list Good Manufacturing Practice or GMP on their labels attest that the products are pure and that they have made efforts to minimize or eliminate contamination and errors. Some manufacturers hire independent laboratories to verify their products’ purity. Not surprisingly, some health care providers and arthritis patients are uncomfortable with this variability in reliability. A supplement labeled as containing 95% curcuminoids may actually contain more or less than the label states. The US Food and Drug Administration does not regulate supplements, so supplement potency may vary from brand to brand and even batch to batch in the manufacturing process.
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Scientists are still learning about what turmeric and curcumin do and how to best harness their natural medicinal capabilities. Scientists are investigating potential supplement additives, such as pepper, that could improve curcumin absorption. Curcumin tends to be rapidly metabolized and is not easily absorbed into the blood stream, which limits its anti-inflammatory and pain-relieving properties. Because curcumin seems to have anti-inflammatory and pain-relieving effects, many people wonder why curcumin supplements are not recommended more often.
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